Protein name:
Transforming growth factor beta-1 (TGF-beta-1) ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
The inactive form consists of a TGFB1 homodimer non-covalently linked to a latency-associated peptide (LAP) homodimer. The inactive complex can contain a latent TGFB1-binding protein. The active form is a homodimer of mature TGFB1; disulfide-linked. Heterodimers of TGFB1/TGFB2 have been found in bone. Interacts with CD109 and DPT. Interacts with ASPN.
Function:
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MPPSGLRLLP | LLLPLLWLLM | LTPGRPVAGL | STCKTIDMEL | VKRKRIEAIR |
100:
GQILSKLRLA | SPPSQGDVPP | GPLPEAILAL | YNSTRDRVAG | ESAETEPEPE |
150:
ADYYAKEVTR | VLMVEYGNKI | YDKMKSSSHS | IYMFFNTSEL | REAVPEPVLL |
200:
SRADVRLLRL | KLKVEQHVEL | YQKYSNNSWR | YLSNRLLAPS | DSPEWLSFDV |
250:
TGVVRQWLTR | REEIEGFRLS | AHCSCDSKDN | TLQVDINGFS | SGRRGDLATI |
300:
HGMNRPFLLL | MATPLERAQH | LHSSRHRRAL | DTNYCFSSTE | KNCCVRQLYI |
350:
DFRKDLGWKW | IHEPKGYHAN | FCLGPCPYIW | SLDTQYSKVL | ALYNQHNPGA |
390:
SAAPCCVPQA | LEPLPIVYYV | GRKPKVEQLS | NMIVRSCKCS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
Pig
Dog
Chicken
Rat
ELISA Kit for Bovine TGF-beta-1
ELISA Kit for Bovine TGF-beta-1
ELISA Kit for Bovine TGF-beta-1
ELISA Kit for Bovine TGF-beta-1
ELISA Kit for Bovine TGF-beta-1
ELISA Kit for Bovine TGF-beta-1
ELISA Kit for Bovine TGF-beta-1
CLIA Kit for Bovine TGF-beta-1
CLIA Kit for Bovine TGF-beta-1
CLIA Kit for Bovine TGF-beta-1
CLIA Kit for Bovine TGF-beta-1
CLIA Kit for Bovine TGF-beta-1
CLIA Kit for Bovine TGF-beta-1
CLIA Kit for Bovine TGF-beta-1
Polyclonal Antibody for Bovine TGF-beta-1
Polyclonal Antibody for Bovine TGF-beta-1
Polyclonal Antibody for Bovine TGF-beta-1
Polyclonal Antibody for Bovine TGF-beta-1
Polyclonal Antibody for Bovine TGF-beta-1
Polyclonal Antibody for Bovine TGF-beta-1
Polyclonal Antibody for Bovine TGF-beta-1
Monoclonal Antibody for Bovine TGF-beta-1
Monoclonal Antibody for Bovine TGF-beta-1
Monoclonal Antibody for Bovine TGF-beta-1
Monoclonal Antibody for Bovine TGF-beta-1
Monoclonal Antibody for Bovine TGF-beta-1
Monoclonal Antibody for Bovine TGF-beta-1
Monoclonal Antibody for Bovine TGF-beta-1
Protein for Bovine TGF-beta-1
Protein for Bovine TGF-beta-1
Protein for Bovine TGF-beta-1
Protein for Bovine TGF-beta-1
Protein for Bovine TGF-beta-1
Protein for Bovine TGF-beta-1
Protein for Bovine TGF-beta-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
Y Abe, M Murano, N Murano, et al.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-118
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 76-390
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT
tissue :
Bone .